![Anti-Human CD4 [OKT-4] In Vivo Antibody - Low Endotoxin](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/1280x1280/products/214347/569314/anti-human-cd4-okt-4-in-vivo-antibody-low-endotoxin__05392.1673496520.jpg?c=2?imbypass=on "Anti-Human CD4 [OKT-4] In Vivo Antibody - Low Endotoxin")
Description
Anti-Human CD4 [OKT-4] In Vivo Antibody - Low Endotoxin
Introducing the Anti-Human CD4 [OKT-4] In Vivo Antibody - Low Endotoxin from Assay Genie, a highly specific monoclonal antibody tailored for in vivo research applications. This antibody accurately targets the CD4 protein, which is integral to the immune response, making it an invaluable tool for studies in immunology and other related disciplines.
With a mouse IgG2b kappa isotype, the Anti-Human CD4 [OKT-4] ensures exceptional purity and minimal endotoxin levels (<1.0 EU/mg), positioning it as an excellent choice for ELISA, flow cytometry, immunohistochemistry, and other sensitive assays. The antibody is available in multiple sizes to fit various experimental needs and is formulated in phosphate-buffered saline to guarantee stability and performance. CD4 is a critical glycoprotein located on the surface of immune cells, including T-helper cells, monocytes, macrophages, and dendritic cells. It plays a pivotal role in the immune system by facilitating the activation of T-cells through its interaction with major histocompatibility complex (MHC) class II molecules. Elevate your research with the reliable and versatile Anti-Human CD4 [OKT-4] In Vivo Antibody - Low Endotoxin from Assay Genie. ---
| Product Name: | Anti-Human CD4 [OKT-4] In Vivo Antibody - Low Endotoxin |
| Product Code: | IVMB0012 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | OKT-4 |
| Protein: | CD4 |
| Product Type: | Monoclonal Antibody |
| Synonyms: | CD4, T4, CD4 antigen (p55), CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 |
| Isotype: | Mouse IgG2b κ |
| Reactivity: | Human |
| Immunogen: | Human peripheral T cells |
| Applications: | ELISA, FC, ICC, IF Staining, IHC FF, IHC FFPE, IP, N, PhenoCycler®, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | CODEX®, ELISA, FC, ICC, IF Staining, IHC FF, IHC FFPE, IP, N, WB |
| Recommended Usage: | ELISA FC WB |
| Reactivity: | Human |
| Host Species: | Mouse |
| Specificity: | Clone OKT4 recognizes Human CD4. This clone recognizes a different epitope than the RPA-T4 monoclonal antibody, and these antibodies do not interfere with each other. |
| Antigen Distribution: | CD4 is expressed on most thymocytes, a subset of T cells, and monocytes/macrophages, and may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. |
| Immunogen: | Human peripheral T cells |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
CD4 is a 55 kD single-chain type I transmembrane glycoprotein and a member of the Ig superfamily. It is involved in the recognition of MHC class II molecules. Furthermore, CD4 is the primary receptor for HIV. CD4 initiates the early phase of T-cell activation via its association with the T-cell receptor complex and protein tyrosine kinase, Lck. In addition, CD4 functions as a mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system.
| Technical Datasheet: | View |
| Protein: | CD4 |
| Research Area: | Immunology |
| Mouse IgG2b Isotype Control | |
|---|---|
| Clone | MPC-11 |
| Isotype | Mouse IgG2b kappa |
| Endotoxin Level | Low Endotoxin |
![Anti-Human CD4 [OKT-4] In Vivo Antibody - Low Endotoxin](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/608x608/products/214347/569314/anti-human-cd4-okt-4-in-vivo-antibody-low-endotoxin__05392.1673496520.jpg?c=2 "Anti-Human CD4 [OKT-4] In Vivo Antibody - Low Endotoxin")
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