Anti-Human CD5 [UCHT-2] In Vivo Antibody - Low Endotoxin
Introducing the Anti-Human CD5 [UCHT-2] In Vivo Antibody - Low Endotoxin from Assay Genie, a highly specific monoclonal antibody tailored for in vivo applications. This antibody targets the CD5 protein, vital in immune response, making it ideal for research in immunology and related disciplines. With a mouse IgG1 isotype, it guarantees high purity and minimal endotoxin levels (<1.0 EU/mg), perfect for ELISA, flow cytometry, immunohistochemistry, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline to ensure stability and efficacy.
Enhance your research with this dependable and versatile antibody. CD5 is a type I transmembrane protein predominantly expressed on the surface of T cells and a subset of B cells. It plays a crucial role in modulating immune responses and ensuring the proper functioning of the immune system through interactions with ligands and other receptors. Make significant strides in your research with the Anti-Human CD5 [UCHT-2] In Vivo Antibody, designed to provide precision and reliability in your experiments.
Product Name:
Anti-Human CD5 (Clone UCHT-2) In Vivo Antibody - Low Endotoxin
Product Code:
IVMB0309
Size:
1 mg, 5 mg, 25 mg, 50 mg, 100 mg
Clone:
UCHT-2
Protein:
CD5
Product Type:
Monoclonal Antibody
Synonyms:
Leu-1, Ly-1, T1, Tp67
Isotype:
IgG1
Reactivity:
Human
Applications:
FA, FC, IHC FF, In Vivo, PhenoCycler®
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Endotoxin Level:
< 1.0 EU/mg as determined by the LAL method
Purity:
≥95% monomer by analytical SEC â‹… >95% by SDS Page
Product Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Applications:
FA, FC, IHC FF, In Vivo, PhenoCycler®
Reactivity:
Human
Host Species:
Mouse
Specificity:
Mouse Anti-Human CD5 (Clone UCHT-2) recognizes Human CD5. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-Human CD5 recognizes a human T-lymphocyte surface membrane antigen (Mr 67 kDa).
Antigen Distribution:
The CD5 antigen is present on approximately 70% of normal peripheral blood lymphocytes and >90% of all T-lymphocytes. T-lymphocytes in the thymus stain weakly while peripheral T-cells stain strongly. Monocytes, granulocytes and NK cells are not stained.1 Anti-CD5 also reacts with a distinct subset of normal B-lymphocytes, occasional cells in B-lymphocyte areas of spleen and lymph node, and most Ig+ B-chronic lymphoblastic leukemia (CLL) cells. The CD5 antigen has also been shown to be present on some lymphomas.
Concentration:
≥ 5.0 mg/ml
Endotoxin Level:
< 1.0 EU/mg as determined by the LAL method
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Purity:
≥95% monomer by analytical SEC â‹… >95% by SDS Page
Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Anti-Human CD5 can be used in research to study B-lymphocyte subsets or characterization of leukemias and lymphomas.
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