The MARK2 Monoclonal Antibody (CAB6512) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit serum, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Mark2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable asset for studies in cell biology and cancer research.Mark2, also known as Par-1c, plays a pivotal role in cell signaling pathways that regulate cell polarity, migration, and cell cycle progression.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
MARK2 Monoclonal Antibody
SKU:
CAB6512
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1862
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
2011
RRID
AB_2863529
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MARK2 Rabbit mAb (CAB6512) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
