Description
Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Low Endotoxin
Introducing the Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Low Endotoxin from Assay Genie, a highly specific monoclonal antibody tailored for in vivo applications. This antibody targets the TNFR2 (Tumor Necrosis Factor Receptor 2), an important receptor in the TNF signaling pathway, making it essential for research in immunology and related disciplines. With a rat IgG1 isotype, it ensures high purity and low endotoxin levels (<1.0 EU/mg), making it perfect for ELISA, flow cytometry, immunohistochemistry, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline for stability and efficacy.
Enhance your research with this reliable and versatile antibody. TNFR2 is a receptor expressed on various cell types, including immune cells such as T-cells, macrophages, and certain types of epithelial cells. It plays a crucial role in the immune system by mediating the effects of TNF, including cell proliferation, differentiation, and survival. This makes the Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Low Endotoxin an invaluable tool for advancing your research in the intricate mechanisms of immune response and inflammation.
| Product Name: | Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Low Endotoxin |
| Product Code: | IVMB0098 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | TR75-54.7 |
| Protein: | TNFR2 |
| Product Type: | Monoclonal Antibody |
| Synonyms: | Tumor Necrosis Factor Receptor II, p75, CD120b, TBPII, TNF-R75, TNFBR, TNFR2, TNFR80, p75TNFR |
| Isotype: | Armenian Hamster IgG |
| Reactivity: | Mouse |
| Immunogen: | Purified Recombinant Mouse TNF R2 |
| Applications: | B, IP, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | B, IP, WB |
| Reactivity: | Mouse |
| Host Species: | Armenian Hamster |
| Specificity: | Anti-Mouse CD120 recognizes Mouse CD120. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Antigen Distribution: | Variety of cell types at low levels |
| Immunogen: | Purified Recombinant Mouse TNF R2 |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Tumor necrosis factor receptor II (TNF-RII) is present on most cell types1 and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells.2
| Technical Datasheet: | View |
| Protein: | TNFR2 |
| Function: | Apoptosis, NF-κB activation, inflammation, tumor necrosis, cell differentiation |
| Ligand/Receptor: | TNF-α, LT-α (TNF-β) |
| Research Area: | Immunology, Innate Immunity |
| Armenian Hamster IgG Isotype Control | |
|---|---|
| Clone | PIP |
| Isotype | Armenian Hamster IgG |
| Endotoxin Level | Low Endotoxin |
