Anti-Mouse IFNγ [XMG1.2] In Vivo Antibody - Ultra Low Endotoxin
Introducing the Anti-Mouse IFNγ [XMG1.2] In Vivo Antibody - Ultra Low Endotoxin from Assay Genie, a highly specific monoclonal antibody engineered for optimal performance in in vivo applications. This antibody targets the interferon-gamma (IFNγ) protein, a critical cytokine in immune regulation, making it indispensable for cutting-edge research in immunology and related fields. Featuring a rat IgG1 isotype, it ensures remarkable purity and ultra-low endotoxin levels (<0.01 EU/μg), suitable for ELISA, flow cytometry, immunohistochemistry, and additional assays. Offered in multiple sizes, it is formulated in a phosphate-buffered saline solution to guarantee stability and efficacy.
Enhance your research with the reliability and versatility of this exceptional antibody. Interferon-gamma is a multifaceted cytokine involved in the immune response, playing a vital role in the activation of macrophages and the stimulation of antigen-presenting cells. It is pivotal for the regulation of innate and adaptive immunity, and its role extends to antiviral and anti-tumor responses, making it a key focus in immunological research.
Product Name:
Anti-Mouse IFNγ (Clone XMG1.2) In Vivo Antibody - Ultra Low Endotoxin
Product Code:
IVMB0368
Size:
1 mg, 5 mg, 25 mg, 50 mg, 100 mg
Clone:
XMG1.2
Protein:
IFN-gamma
Product Type:
Monoclonal Antibody
Synonyms:
Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI
Isotype:
IgG1 k
Reactivity:
Mouse
Applications:
CyTOF®, ELISA Cap, ELISPOT, ICFC, IHC FF, In Vivo, N, WB
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Endotoxin Level:
≤ 0.5 EU/mg as determined by the LAL method
Purity:
≥98% monomer by analytical SEC ⋅ >95% by SDS Page
Product Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Applications:
CyTOF®, ELISA Cap, ELISPOT, ICFC, IHC FF, In Vivo, N, WB
Reactivity:
Mouse
Host Species:
Rat
Specificity:
Rat Anti-Mouse Interferon Gamma (IFN-gamma) (Clone XMG1.2) recognizes an epitope on Mouse IFN-gamma. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Immunogen:
Purified Recombinant Mouse IFN-gamma (>98%)
Concentration:
≥ 5.0 mg/ml
Endotoxin Level:
≤ 0.5 EU/mg as determined by the LAL method
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Purity:
≥98% monomer by analytical SEC ⋅ >95% by SDS Page
Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Interferon-gamma (IFN-gamma) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-gamma has antiviral, immunoregulatory, and anti-tumour properties.3
To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Assay Genie's Purified Functional Antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile.
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