The Placental lactogen (CSH1) Monoclonal Antibody (CAB19258) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is specifically designed for use in immunohistochemistry and other research applications. It is highly reactive with human samples, allowing for accurate detection and analysis of CSH1 in various tissues and cell types.CSH1 is a hormone produced by the placenta during pregnancy and plays a crucial role in regulating maternal metabolism and fetal growth. Research into CSH1 can provide valuable insights into pregnancy-related disorders, such as preeclampsia and gestational diabetes, as well as potential therapeutic targets for treating these conditions.
This antibody is validated for use in ELISA, IF-P applications and has demonstrated reactivity against Human samples.
Product Name:
Placental lactogen (CSH1) Monoclonal Antibody
SKU:
CAB19258
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC2426
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.
Purification Method
Affinity purification
Gene ID
1442
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Immunofluorescence analysis of paraffin-embedded human placenta using Placental lactogen (CSH1) (CSH1) Rabbit mAb (CAB19258) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
