The p16-ARC/ARC16/ARPC5 Antibody (CAB8571) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and other applications.ARPC5 plays a crucial role in cell motility, specifically in the formation of branched actin networks that are essential for cell migration and other cellular processes. Dysregulation of ARPC5 expression has been implicated in various diseases, including cancer and neurological disorders, making it an attractive target for therapeutic interventions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
p16-ARC/ARC16/ARPC5 Antibody
SKU:
CAB8571
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ARC16, p16-Arc, dJ127C7.3, p16-ARC/ARC16/ARPC5
Positive Sample:
Mouse spleen, Mouse small intestine, Rat brain
Cellular Localization:
Cell Projection, Cytoplasm, Cytoskeleton.
Calculated MW:
16kDa
Observed MW:
18kDa
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Purification Method
Affinity purification
Gene ID
10092
RRID
AB_2768456
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using p16-ARC/ARC16/ARPC5 Rabbit pAb (CAB8571) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
