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Biotin Anti-Human CD19 Antibody [CB19] (AGEL2779)

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SKU AGEL2779
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone CB19
Conjugation Biotin
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Description

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Biotin Anti-Human CD19 Antibody [CB19]

The Biotin Anti-Human CD19 Antibody (CB19) offered by Assay Genie is a versatile tool for research applications focused on CD19, a crucial cell surface protein found primarily on B cells. This antibody, optimized for human samples, is raised against CD19 and has been validated for use in various immunoassays, including flow cytometry and immunohistochemistry.CD19, a key component of the B cell receptor complex, plays a pivotal role in B cell development, activation, and differentiation. Its expression pattern and functional significance make it a valuable marker for identifying and studying B cells in both normal and disease states, particularly in hematological malignancies such as leukemia and lymphoma.

The Biotin Anti-Human CD19 Antibody (CB19) from Assay Genie offers high specificity and sensitivity, making it an essential tool for researchers exploring the role of CD19 in immunology, oncology, and autoimmune diseases. With its reliable performance and broad applicability, this antibody is ideal for investigations aimed at understanding B cell biology and developing targeted therapies for CD19-related conditions.

Product Title:Biotin Anti-Human CD19 Antibody [CB19]
SKU:AGEL2779
Size:25µg, 100µg
Clone No:CB19
Synonyms:B-lymphocyte antigen CD19;Cd19;Differentiation antigen CD19;CD19;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P15391
Gene ID:930
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.

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