The BRK1 Polyclonal Antibody (CAB17182) is a valuable tool for researchers studying BRK1, a protein involved in cell signaling and cancer progression. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the BRK1 protein, this antibody allows for the detection and analysis of BRK1 expression in various cell types, making it useful for studies in cancer biology and molecular biology.BRK1, also known as breast tumor kinase, is a key player in signaling pathways that regulate cell growth and survival. Its overexpression has been linked to the development and progression of breast and ovarian cancers, making it a promising target for therapeutic interventions.
By studying the function of BRK1, researchers can gain insight into the mechanisms driving cancer growth and potentially identify new targets for anti-cancer therapies.Overall, the BRK1 Polyclonal Antibody (CAB17182) offers researchers a reliable tool for investigating the role of BRK1 in cancer biology and cell signaling pathways. Its high specificity and sensitivity make it an essential component for any research project focused on understanding the molecular mechanisms underlying cancer development and progression.
Product Name:
BRK1 Rabbit Polyclonal Antibody
SKU:
CAB17182
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human BRK1 (NP_060932.2).
Enables identical protein binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction and positive regulation of cellular component organization. Located in extracellular exosome. Part of SCAR complex.
Purification Method:
Affinity purification
Gene ID:
55845
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human breast cancer using BRK1 Rabbit pAb (CAB17182) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
