Description
CACNA1D Antibody (CAB16785)
The CACNA1D Antibody (CAB16785) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the CACNA1D protein, this antibody enables the detection and analysis of CACNA1D expression in a variety of cell types, making it ideal for studies in neuroscience, cardiovascular research, and beyond.CACNA1D, also known as the voltage-gated calcium channel Cav1.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
| Product Name: | CACNA1D Antibody |
| SKU: | CAB16785 |
| Size: | 20μL, 100μL |
| Reactivity: | Human, Rat |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | RQNY GYYS RYPG RNID SERP RGYH HPQG FLED DDSP VCYD SRRS PRRR LLPP TPAS HRRS SFNF ECLR RQSS QEEV PSSP IFPH RTAL PLHL MQQQ IMAV AGLD SSKA QKYS PSHS TRSW ATPP ATPP YRDW TPCY TPLI QVEQ SEAL DQVN GSLP SLHR SSWY TDEP DISY RTFT PASL TVPS SFRN KNSD KQRS ADSL VEAV LISE GLGR YARD PKFV SATK HEIA DACD LTID EMES AAST LLNG NVRP RANG DVGP LSHR QDYE LQDF GPGY SDEE PDPG RDEE DLAD EMIC ITTL | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | CACH3, CACN4, PASNA, SANDD, Cav1.3, CCHL1A2, CACNL1A2, CACNA1D |
| Positive Sample: | Rat kidney |
| Cellular Localization: | Membrane, Multi-Pass Membrane Protein. |
| Calculated MW: | 245kDa |
| Observed MW: | 245kDa |
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.
| Purification Method | Affinity purification |
| Gene ID | 776 |
| RRID | AB_2768671 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from Rat kidney, using CACNA1D Rabbit pAb (CAB16785) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s. |
