The CALCR Polyclonal Antibody (CAB10674) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the CALCR protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in molecular biology and physiology.CALCR, also known as calcitonin receptor, is a key player in calcium homeostasis and bone metabolism. Its ability to bind with calcitonin and other ligands makes it a crucial component in regulating calcium levels and bone remodeling.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
CALCR Polyclonal Antibody
SKU:
CAB10674
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CRT, CTR, CT-R, CTR1, CALCR
Positive Sample:
T-47D, MCF7
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
55kDa
Observed MW:
70kDa
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
799
RRID
AB_2768685
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using CALCR Rabbit pAb (CAB10674) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
