The Cathepsin E Polyclonal Antibody (CAB2678) is a valuable tool for researchers studying Cathepsin E, a lysosomal proteinase involved in protein degradation and antigen processing. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. Cathepsin E is known to play a crucial role in the immune system by processing antigens for presentation to T cells and regulating immune responses. It is also implicated in various pathological conditions, including cancer and autoimmune diseases.
The Cathepsin E Polyclonal Antibody binds specifically to the Cathepsin E protein, allowing for precise detection and analysis in a variety of cell types.Researchers studying immunology, cancer biology, and antigen processing will find the Cathepsin E Polyclonal Antibody an essential tool for their studies. By understanding the function and regulation of Cathepsin E, researchers may uncover new insights into immune responses and potentially develop novel therapeutic strategies for various diseases.
Product Name:
CTSE Rabbit Polyclonal Antibody
SKU:
CAB2678
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 132-244 of human Cathepsin E (CTSE) (P14091).
This gene encodes a member of the A1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme, an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration.
Purification Method:
Affinity purification
Gene ID:
1510
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cathepsin E (CTSE) Rabbit pAb (CAB2678) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
