CBY1 Antibody, FITC conjugated (PACO64089)
- SKU:
- PACO64089
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- FITC
Description
CBY1 Antibody, FITC conjugated (PACO64089)
The CBY1 Antibody FITC Conjugated (PACO64089) is a specialized antibody designed for research involving CBY1, a protein involved in various cellular processes. This antibody, conjugated with FITC for fluorescent detection, is raised in rabbits and is highly reactive with human samples. It is validated for use in flow cytometry applications, enabling the specific detection and analysis of CBY1 in different cell types.CBY1 is known to play a role in cell signaling, protein trafficking, and regulation of cellular growth and differentiation.
By targeting CBY1 with this antibody, researchers can gain valuable insights into its function and potential implications in diseases such as cancer, neurological disorders, and metabolic diseases. With the ability to detect CBY1 in cells, this antibody is a powerful tool for studies in cell biology, molecular biology, and disease mechanism research.
| Antibody Name: | CBY1 Antibody?FITC conjugated (PACO64089) |
| Antibody SKU: | PACO64089 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein chibby homolog 1 protein (41-126AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Antigen Affinity purified & Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | FITC |
| Background: | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. |
| Synonyms: | Protein chibby homolog 1 (ARPP-binding protein) (Cytosolic leucine-rich protein) (PIGEA-14) (PKD2 interactor, Golgi and endoplasmic reticulum-associated 1), CBY1, ARB1 C22orf2 CBY PGEA1 |
| UniProt Protein Function: | CBY1: Inhibits the Wnt/Wingless pathway by binding to beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. Belongs to the chibby family.Protein type: Transcription regulationChromosomal Location of Human Ortholog: 22q12Cellular Component: cytosol; nucleoplasm; nucleus; trans-Golgi networkMolecular Function: beta-catenin binding; identical protein binding; protein bindingBiological Process: cardiac muscle cell differentiation; fat cell differentiation; negative regulation of transcription, DNA-dependent; negative regulation of Wnt receptor signaling pathway; protein localization |
| UniProt Protein Details: | |
| NCBI Summary: | Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y3M2 |
| NCBI GenInfo Identifier: | 20454882 |
| NCBI Gene ID: | 25776 |
| NCBI Accession: | Q9Y3M2.1 |
| UniProt Secondary Accession: | Q9Y3M2,Q66GT6, Q9UIK9, B2R4S2 |
| UniProt Related Accession: | Q9Y3M2 |
| Molecular Weight: | 14,470 Da |
| NCBI Full Name: | Protein chibby homolog 1 |
| NCBI Synonym Full Names: | chibby family member 1, beta catenin antagonist |
| NCBI Official Symbol: | CBY1 |
| NCBI Official Synonym Symbols: | CBY; arb1; PGEA1; C22orf2; PIGEA14; PIGEA-14; HS508I15A |
| NCBI Protein Information: | protein chibby homolog 1 |
| UniProt Protein Name: | Protein chibby homolog 1 |
| UniProt Synonym Protein Names: | ARPP-binding protein; Cytosolic leucine-rich protein; PIGEA-14; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 |
| Protein Family: | Protein chibby |
| UniProt Gene Name: | CBY1 |
| UniProt Entry Name: | CBY1_HUMAN |
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