The CD4 Polyclonal Antibody (CAB23259) is an essential tool for researchers studying the CD4 protein, a key marker of T helper cells in the immune system. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CD4 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an ideal choice for immunology and cancer research studies.CD4, also known as the T-cell surface glycoprotein, plays a crucial role in the immune response by facilitating communication between cells and assisting in the activation of immune responses.
Research into the function and regulation of CD4 is essential for understanding various diseases, including autoimmune disorders, infectious diseases, and cancer. The CD4 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of CD4 in these conditions and developing potential therapeutic interventions.
Product Name:
CD4 Polyclonal Antibody
SKU:
CAB23259
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant protein of mouse CD4.
Tested Applications:
WBIF/ICCELISA
Recommended Dilution:
WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:
L3T4; Ly-4; CD4
Positive Sample:
Mouse thymus
Conjugate:
Unconjugated
Calculated MW:
51kDa
Observed MW:
55kDa
Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).
Purification Method:
Affinity purification
Gene ID:
12504
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Mouse thymus, using CD4 Rabbit pAb (CAB23259) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
