The CDH19 Polyclonal Antibody (CAB14584) is a valuable tool for researchers studying CDH19, a cell adhesion molecule known for its role in cell-cell adhesion and signaling processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications including Western blot and immunohistochemistry.CDH19, also referred to as cadherin-19, is involved in cell adhesion mechanisms that play a crucial role in tissue organization and development.
Dysregulation of CDH19 expression has been implicated in various diseases including cancer, making it a promising target for therapeutic intervention. By enabling the specific detection and analysis of CDH19 protein levels in different cell types, this polyclonal antibody serves as an essential tool for understanding the molecular mechanisms underlying disease progression and for advancing research in the fields of oncology and developmental biology.
Product Name:
CDH19 Rabbit Polyclonal Antibody
SKU:
CAB14584
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-440 of human CDH19 (NP_066976.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
87kDa
Observed MW:
87kDa
This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene.
Purification Method:
Affinity purification
Gene ID:
28513
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDH19 Rabbit pAb (CAB14584) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
