The Cadherin-2 Polyclonal Antibody (CAB0432) is a valuable tool for researchers studying Cadherin-2, a cell adhesion molecule important for cell-cell interactions and tissue organization. This antibody, generated in rabbits, is highly specific for Cadherin-2 in human samples and is suitable for use in Western blot applications. Cadherin-2, also known as N-cadherin, plays a crucial role in cell adhesion and migration, making it a key player in processes like embryonic development, wound healing, and cancer metastasis. The Cadherin-2 Polyclonal Antibody enables the detection and analysis of Cadherin-2 in various cell types, making it an essential tool for researchers in the fields of developmental biology, cancer biology, and regenerative medicine.
By studying the expression and function of Cadherin-2, researchers can gain valuable insights into cell behavior, tissue development, and disease progression. The Cadherin-2 Polyclonal Antibody is a reliable reagent for investigating the role of Cadherin-2 in various physiological and pathological processes, ultimately contributing to advancements in biomedicine and therapeutics.
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
100kDa
Observed MW:
120kDa
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.
Purification Method:
Affinity purification
Gene ID:
1000
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using N-Cadherin Rabbit pAb (CAB0432) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
