The CDK10 Antibody (CAB2690) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-raised antibody is specially designed for use in Western blot applications and is highly reactive with human samples.CDK10, a member of the CDK family, plays a crucial role in controlling cell division and gene transcription processes. Its dysregulation has been linked to various diseases, including cancer. By targeting the CDK10 protein, researchers can effectively study its function and regulation in different cell types, providing important insights into its potential roles in disease development and treatment.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
CDK10 Antibody
SKU:
CAB2690
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ALSAS, PISSLRE, CDK10
Positive Sample:
293T, HT-29
Cellular Localization:
Ciliary Basal Body, Cytoplasm, Nucleus.
Calculated MW:
41kDa
Observed MW:
46kDa
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
8558
RRID
AB_2764549
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CDK10 Rabbit pAb (CAB2690) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
