Description
system_update_altDatasheet
| Product Name: | CDw131 monoclonal antibody |
| Product Code: | AGIM0003 |
| Size: | 100 µg in 100 µL |
| Reactivity: | Human |
| Clone: | 1C1 |
| Applications: | Flow Cytometry |
| Conjugate: | Unconjugated |
| Isotype: | IgG1,k |
| Host Species: | Mouse |
| Storage: | Store at -20°C. |
| Uniprot: | P32927 |
| UniProt Protein Function: | CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, cytokine Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane Molecular Function:interleukin-3 receptor activity; interleukin-5 receptor activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor activity Biological Process: cellular protein metabolic process; MAPKKK cascade; respiratory gaseous exchange Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5 |
| NCBI Summary: | The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008] |
| UniProt Code: | P32927 |
| NCBI GenInfo Identifier: | 1345923 |
| NCBI Gene ID: | 1439 |
| NCBI Accession: | P32927.2 |
| UniProt Secondary Accession: | P32927,Q5JZI1, Q6ICE0, |
| UniProt Related Accession: | P32927 |
| Molecular Weight: | 97,976 Da |
| NCBI Full Name: | Cytokine receptor common subunit beta |
| NCBI Synonym Full Names: | colony stimulating factor 2 receptor beta common subunit |
| NCBI Official Symbol: | CSF2RBÂ Â |
| NCBI Official Synonym Symbols: | CD131; IL3RB; IL5RB; SMDP5; CDw131Â Â |
| NCBI Protein Information: | cytokine receptor common subunit beta |
| UniProt Protein Name: | Cytokine receptor common subunit beta |
| UniProt Synonym Protein Names: | CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131 |
| Protein Family: | Cytokine receptor |
| UniProt Gene Name: | CSF2RBÂ Â |
| UniProt Entry Name: | IL3RB_HUMAN |
