The CLPP Polyclonal Antibody (AB10022) is a valuable tool for researchers studying the CLPP protein, a key component of the mitochondrial ClpXP protease complex involved in protein degradation. This antibody, produced in rabbits, is highly specific for detecting CLPP in human samples and is recommended for use in Western blot applications.CLPP is essential for maintaining mitochondrial function and cellular homeostasis, making it a significant target for research in the fields of cell biology and metabolism. Dysregulation of CLPP has been linked to various diseases, including metabolic disorders and neurological conditions, making it a promising target for therapeutic interventions.
By using the CLPP Polyclonal Antibody, researchers can accurately detect and analyze CLPP expression in different cell types, providing valuable insights into the role of this protein in health and disease. This antibody is a versatile tool for studies exploring mitochondrial function, protein degradation pathways, and potential therapeutic strategies for CLPP-related conditions.
Product Name:
CLPP Polyclonal Antibody
SKU:
CAB21670
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human CLPP (NP_006003.1).
The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane.
Purification Method:
Affinity purification
Gene ID:
8192
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CLPP Rabbit pAb (CAB21670) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
