The CLPX Polyclonal Antibody (CAB17088) is a valuable tool for research involving CLPX, a key protein involved in cellular processes such as protein folding and quality control. This rabbit-derived antibody is highly specific and suitable for use in Western blot applications, allowing for the detection and analysis of CLPX in various biological samples.CLPX is a vital component of the ClpX-ClpP proteolytic complex, which plays a crucial role in protein degradation and turnover within the cell. Dysfunction of CLPX has been implicated in various diseases, highlighting its importance in cellular homeostasis.
By utilizing the CLPX Polyclonal Antibody, researchers can further explore the function and regulation of this protein, leading to insights into potential therapeutic targets for conditions related to protein homeostasis disorders. Overall, the CLPX Polyclonal Antibody is a reliable tool for researchers in the fields of molecular biology, biochemistry, and cell biology, offering a precise and sensitive method for studying the role of CLPX in cellular processes.
Product Name:
CLPX Polyclonal Antibody
SKU:
CAB17088
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human CLPX (NP_006651.2).
The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10845
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CLPX Rabbit pAb (CAB17088) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
