The CMTM2 Polyclonal Antibody (PAC014252) is a valuable tool for researchers studying CMTM2, a protein involved in immune regulation and cancer development. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blotting applications. By binding to the CMTM2 protein, this antibody enables the detection and analysis of CMTM2 in various cell types, making it an ideal choice for immunology and cancer research studies.CMTM2, also known as CKLF-like MARVEL transmembrane domain-containing protein 2, has been implicated in regulating immune responses and promoting tumor growth in various cancer types.
Understanding the role of CMTM2 in immune modulation and oncogenesis is essential for developing targeted therapies for cancer and autoimmune diseases. The CMTM2 Polyclonal Antibody offers researchers a reliable tool for investigating the functions and mechanisms of CMTM2, ultimately leading to new insights in the field of cancer biology and immunotherapy.
Antibody Name:
CMTM2 Antibody (PACO14252)
Antibody SKU:
PACO14252
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Fusion protein of human CMTM2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14252(CMTM2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14252(CMTM2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development.
CMTM2: a member of the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008]
UniProt Protein Details:
Protein type:Membrane protein, integral; Nuclear receptor co-regulator; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: nucleoplasm; extracellular space; integral to membrane
Molecular Function:cytokine activity
Biological Process: chemotaxis
NCBI Summary:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008]
