The COA3 Polyclonal Antibody (CAB14585) is a valuable tool for researchers studying COA3, a protein involved in mitochondrial function and metabolism. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to COA3, this antibody allows for the detection and analysis of this protein in various cellular contexts, making it ideal for studies in mitochondrial biology and energy metabolism.COA3, also known as cytochrome c oxidase assembly factor 3, is essential for the proper assembly and function of cytochrome c oxidase, a key enzyme in the electron transport chain of mitochondria.
Dysregulation of COA3 has been implicated in various metabolic disorders and diseases, highlighting the importance of studying its role in cellular energy production. The COA3 Polyclonal Antibody offers researchers a reliable tool for investigating the function and regulation of this critical mitochondrial protein.
Product Name:
COA3 Rabbit Polyclonal Antibody
SKU:
CAB14585
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human COA3 (NP_001035521.1).
This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase function.
Purification Method:
Affinity purification
Gene ID:
28958
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using COA3 Rabbit pAb (CAB14585) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
