The CORIN Antibody (CAB10404) is a high-quality antibody developed for reliable detection and analysis of target proteins. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. RRID AB_2757953 Gene ID 10699 Swiss Prot Synonym CRN; ATC2; Lrp4; PEE5; TMPRSS10; CORIN
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
CORIN Antibody
SKU:
CAB10404
Size:
100μL, 20μL
Reactivity:
Human, Mouse, Rat
Clone Number:
-
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CRN, ATC2, Lrp4, PEE5, TMPRSS10, CORIN
Positive Sample:
HeLa, HepG2, A-549, U-251MG, Mouse liver, Rat brain
Cellular Localization:
Cell Membrane, Secreted, Single-Pass Type Ii Membrane Protein, Single-Pass Type Ii Membrane Protein.
Calculated MW:
116kDa
Observed MW:
116kDa
This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. RRID AB_2757953 Gene ID 10699 Swiss Prot Synonym CRN; ATC2; Lrp4; PEE5; TMPRSS10; CORIN
Purification Method:
Affinity purification
Gene ID:
10699
RRID:
AB_2757953
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CORIN Rabbit pAb (CAB10404) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
