The CRMP1 Monoclonal Antibody (CAB2390) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples, making it ideal for various research applications, including Western blotting.CRMP1, also known as collapsin response mediator protein 1, is crucial for axon guidance and neuronal differentiation, making it a key player in nervous system development. Dysregulation of CRMP1 has been linked to neurological disorders such as Alzheimer's disease and schizophrenia, highlighting the importance of studying this protein in the context of neurobiology.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
CRMP1 Monoclonal Antibody
SKU:
CAB2390
Size:
20μL, 100μL
Reactivity:
Human, Rat
Clone Number:
ARC1918
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
DRP1, DRP-1, CRMP-1, DPYSL1, ULIP-3, CRMP1
Positive Sample:
RD, C6
Cellular Localization:
Cytoplasm, Centrosome, Cytoskeleton, Microtubule Organizing Center, Spindle.
Calculated MW:
62kDa
Observed MW:
62kDa
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
1400
RRID
AB_2770781
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using CRMP1 Rabbit mAb (CAB2390) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
