The CSDE1 Polyclonal Antibody (CAB20001) is a valuable tool for researchers studying CSDE1, a protein involved in RNA metabolism and cellular processes such as mRNA splicing and translation. This rabbit-derived antibody is highly specific and reactive with human samples, making it ideal for Western blot and immunohistochemistry applications.CSDE1, also known as cold shock domain-containing protein E1, plays a crucial role in post-transcriptional gene regulation and is implicated in various biological processes, including cell proliferation and differentiation. Dysregulation of CSDE1 has been linked to cancer and neurodegenerative diseases, highlighting its importance in cellular homeostasis.
By utilizing the CSDE1 Polyclonal Antibody, researchers can investigate the expression and localization of CSDE1 in different cell types and tissues, providing valuable insights into its function and potential therapeutic targets. This antibody is a reliable tool for studies in molecular biology, cancer research, and developmental biology, aiding in the understanding of disease mechanisms and target identification for future therapeutic interventions.
Product Name:
[KO Validated] CSDE1 Rabbit Polyclonal Antibody
SKU:
CAB20001
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 369-600 of human CSDE1 (NP_009089.4).
Enables RNA stem-loop binding activity. Involved in IRES-dependent viral translational initiation; nuclear-transcribed mRNA catabolic process, no-go decay; and stress granule assembly. Located in Golgi apparatus; cytosol; and plasma membrane. Part of CRD-mediated mRNA stability complex.
Purification Method:
Affinity purification
Gene ID:
7812
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and CSDE1 knockout (KO) HeLa cells, using [KO Validated] CSDE1 Rabbit pAb (CAB20001) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
