The DCAF17 Antibody (CAB17776) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit polyclonal antibody is highly specific to human samples and is suitable for use in Western blot applications. By binding to the DCAF17 protein, this antibody enables the detection and analysis of DCAF17 in various cell types, making it an essential tool for studying cell cycle regulation and protein degradation mechanisms.DCAF17, also known as DDB1- and CUL4-associated factor 17, plays a crucial role in targeting specific substrates for degradation through the CUL4-DDB1 E3 ubiquitin ligase complex.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.
Product Name:
DCAF17 Antibody
SKU:
CAB17776
Size:
20μL, 100μL
Reactivity:
Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
C2orf37, C20orf37, DCAF17
Positive Sample:
Rat spleen, Rat lung
Cellular Localization:
Cytosol, Nucleolus, Nucleoplasm.
Calculated MW:
59kDa
Observed MW:
59kDa
This gene encodes a nuclear transmembrane protein that associates with cullin 4A/damaged DNA binding protein 1 ubiquitin ligase complex. Mutations in this gene are associated with Woodhouse-Sakati syndrome. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
80067
RRID
AB_2769116
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCAF17 Rabbit pAb (CAB17776) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
