The DDX46 Polyclonal Antibody (CAB4350) is a versatile tool for researchers studying the DDX46 protein, a key player in RNA metabolism and RNA-related processes. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it a reliable option for Western blot applications. By specifically binding to the DDX46 protein, researchers can effectively detect and analyze its expression in various cell types, allowing for in-depth investigations into its functions in molecular biology and cancer research.
DDX46 is an essential RNA helicase involved in RNA splicing, translation, and RNA degradation, making it a crucial component in gene expression regulation. Dysregulation of DDX46 has been associated with various pathologies, including cancer and neurodegenerative diseases, highlighting its potential as a therapeutic target. The DDX46 Polyclonal Antibody is a valuable tool for unraveling the intricate roles of DDX46 in cellular processes, paving the way for novel insights and advancements in biomedical research.
Product Name:
DDX46 Rabbit Polyclonal Antibody
SKU:
CAB4350
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 682-1031 of human DDX46 (NP_055644.2).
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9879
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DDX46 Rabbit pAb (CAB4350) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
