The DHRS1 Polyclonal Antibody (PACO03402) is a valuable tool for researchers studying DHRS1, a key enzyme involved in the metabolism of retinoids and steroids. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it suitable for use in various applications such as Western blotting. By targeting the DHRS1 protein, this antibody allows for the precise detection and analysis of DHRS1 expression in different cell types, providing crucial insights for studies in metabolism and hormone signaling pathways.DHRS1, also known as dehydrogenase/reductase SDR family member 1, plays a crucial role in the regulation of retinoic acid and steroid hormone metabolism, impacting processes such as cell differentiation, proliferation, and apoptosis.
Dysregulation of DHRS1 has been linked to various diseases, including cancer and metabolic disorders, highlighting its potential as a therapeutic target. By investigating the function of DHRS1 using this antibody, researchers can advance their understanding of these diseases and potentially identify new treatment strategies.
Antibody Name:
DHRS1 Antibody
Antibody SKU:
PACO03402
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human DHRS1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
DHRS1; Dehydrogenase/reductase SDR family member 1
UniProt Protein Function:
DHRS1: a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]Protein type: Oxidoreductase; EC 1.1.-.-; Endoplasmic reticulum; MitochondrialChromosomal Location of Human Ortholog: 14q12Cellular Component: endoplasmic reticulumMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
