The DUSP2 Polyclonal Antibody (CAB16366) is a vital tool for researchers studying the dual specificity phosphatase 2 (DUSP2) protein. This antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to the DUSP2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for studies in molecular biology and oncology research.DUSP2 is a key regulator of cell proliferation and differentiation, making it a promising target for investigations into cancer progression and therapy development.
The ability of DUSP2 to modulate signaling pathways involved in cell growth and survival underscores its potential as a therapeutic target for cancer treatment. Researchers aiming to unravel the complex mechanisms of cell signaling pathways can leverage the specificity and reliability of the DUSP2 Polyclonal Antibody for their experiments, ultimately advancing our understanding of cancer biology.
Product Name:
DUSP2 Rabbit Polyclonal Antibody
SKU:
CAB16366
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human DUSP2 (NP_004409.1).
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.
Purification Method:
Affinity purification
Gene ID:
1844
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DUSP2 Rabbit pAb (CAB16366) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
