The EFHC1 Antibody (CAB8002) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.EFHC1 is known to play a role in neuronal development and function, and mutations in the EFHC1 gene have been linked to several types of epilepsy. By targeting EFHC1 with this antibody, researchers can detect and analyze the protein in different cell types, shedding light on its function and potential implications for neurological disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
EFHC1 Antibody
SKU:
CAB8002
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
EJM1, POC9, RIB72, dJ304B14.2, EFHC1
Positive Sample:
HeLa, Mouse testis, Mouse brain
Cellular Localization:
Cytoplasm, Centrosome, Cytoskeleton, Microtubule Organizing Center, Spindle.
Calculated MW:
74kDa
Observed MW:
74kDa
This gene encodes an EF-hand-containing calcium binding protein. The encoded protein likely plays a role in calcium homeostasis. Mutations in this gene have been associated with susceptibility to juvenile myoclonic epilepsy and juvenile absence epilepsy. Alternatively spliced transcript variants have been described.
Purification Method
Affinity purification
Gene ID
114327
RRID
AB_2769269
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using EFHC1 Rabbit pAb (CAB8002) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
