The EPSTI1 Polyclonal Antibody (PAC016264) is a valuable tool for researchers studying EPSTI1, a protein involved in immune regulation and inflammatory responses. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the EPSTI1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology, oncology, and inflammation research.EPSTI1, also known as interferon-inducible protein 1, is a key player in the immune response, particularly in the context of viral infections and inflammatory diseases.
Its role in regulating immune signaling pathways and modulating inflammatory processes highlights its potential as a therapeutic target for conditions such as viral infections, autoimmune disorders, and inflammatory conditions. Research into the function of EPSTI1 is essential for developing targeted therapies that can effectively modulate immune responses in these disease states.
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO16264(EPSTI1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: PACO16264(EPSTI1 Antibody) at dilution 1/1900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16264(EPSTI1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
EPSTI1 (Epithelial-stromal interaction protein 1), also known as BRESI1, is a 318 amino acid, protein that is highly expressed in spleen, placenta, small intestine, liver, kidney, thymus, testis and salivary gland. Existing as three isoforms that are formed due to alternative splicing events, EPSTI1 is weakly expressed in normal breast tissue, but is heavily up-regulated in breast carcinoma, suggesting an important role for EPSTI1 in tumor formation and/or progression. Additionally, EPSTI1 is found in blood cells from systemic lupus erythematosus (SLE)-afflicted patients, implicating EPSTI1 as a potential protein involved in SLE.
Synonyms:
epithelial stromal interaction 1
UniProt Protein Function:
EPSTI1: 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 13q13.3
