The EXOC3 Antibody (CAB17635) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific and sensitive, making it ideal for experiments requiring precise detection of EXOC3 in various sample types.EXOC3 plays a crucial role in the regulation of vesicle transport and secretion processes within cells, making it an important target for investigation in cell biology and neurobiology research. The antibody is validated for use in Western blotting and immunofluorescence applications, providing researchers with reliable results and clear visualization of EXOC3 expression in experimental settings.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
EXOC3 Antibody
SKU:
CAB17635
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SEC6, Sec6p, SEC6L1, EXOC3
Positive Sample:
PC-3, U-251MG, Mouse brain, Mouse lung, Rat brain
Cellular Localization:
Cytosol, Exocyst, Golgi Apparatus, Growth Cone, Perinuclear Region Of Cytoplasm, Presynaptic Membrane.
Calculated MW:
86kDa
Observed MW:
87kDa
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Purification Method
Affinity purification
Gene ID
11336
RRID
AB_2769377
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXOC3 Rabbit pAb (CAB17635) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5min.
