The FAF1 Polyclonal Antibody (CAB7779) is a crucial tool for researchers studying Fas-associated factor 1 (FAF1), a protein involved in regulating cell death and apoptosis. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the FAF1 protein, this antibody enables detection and analysis in a variety of cell types, making it ideal for research in cell biology and cancer studies.FAF1 is known to play a vital role in apoptosis, cell cycle regulation, and tumorigenesis, making it a promising target for therapeutic interventions in cancer treatment.
Understanding the function and regulation of FAF1 is essential for developing novel therapies that target cell death pathways and inhibit cancer progression. The FAF1 Polyclonal Antibody is a valuable tool for researchers aiming to uncover the mechanisms underlying cell death and survival pathways, paving the way for innovative cancer treatments.
Product Name:
FAF1 Rabbit Polyclonal Antibody
SKU:
CAB7779
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide of human FAF1
Tested Applications:
WBIHC-PELISA
Recommended Dilution:
WB,1:500 - 1:2000 IHC-P,1:100 - 1:200
Synonyms:
hFAF1; CGI-03; HFAF1s; UBXD12; UBXN3A; FAF1
Positive Sample:
HeLa,HL-60,SW620,Mouse testis
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
74kDa
Observed MW:
74kDa
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
Purification Method:
Affinity purification
Gene ID:
11124
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using FAF1 Rabbit pAb (CAB7779) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
