The Anti-FGL1 Antibody (CAB20335) is a valuable tool for researchers studying Fibrinogen Like Protein 1 (FGL1), a protein involved in immune regulation and cancer progression. This polyclonal antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications.FGL1 is known to play a role in immune modulation and has been implicated in promoting tumor growth and metastasis in various cancer types. This antibody binds specifically to the FGL1 protein, enabling researchers to detect and analyze its expression in different cell types, making it ideal for studies in immunology and cancer research.
Understanding the function of FGL1 is crucial for developing targeted therapies for cancer and other diseases where immune regulation plays a significant role. By studying the interactions of FGL1 with immune cells and tumor microenvironments, researchers can gain insights into potential therapeutic targets and biomarkers for the development of novel treatment strategies.
Product Name:
FGL1 Rabbit Monoclonal Antibody
SKU:
CAB20335
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant protein of human FGL-1 Full length (NP_004458.3).
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
Purification Method:
Affinity purification
Gene ID:
2267
Clone Number:
ARC5134-01
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using FGL1 antibody (CAB20335) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
