The Filamin A Monoclonal Antibody (CAB3738) is a high-quality antibody developed for reliable detection and analysis of target proteins. This high-quality antibody, developed in rabbits, is specifically designed to target Filamin A in human samples and is validated for use in Western blot applications. By binding to Filamin A, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential tool for studies in cell biology, signal transduction, and disease mechanisms.Filamin A is a crucial protein that plays a significant role in cell adhesion, migration, and cytoskeletal organization.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
Filamin A Monoclonal Antibody
SKU:
CAB3738
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC0242
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
2316
RRID
AB_2863133
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Filamin A Rabbit mAb (CAB3738) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
