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FITC Anti-Human/Mouse KLRG-1 Antibody [2F1] (AGEL3107)

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SKU AGEL3107
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Reactivity Mouse
Host Species Syrian Hamster
Isotype Syrian Hamster IgG
Clone 2F1
Conjugation FITC
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Description

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FITC Anti-Human/Mouse KLRG-1 Antibody [2F1]

The FITC Anti-Human/Mouse KLRG-1 Antibody (2F1) is a versatile tool designed for research involving KLRG-1, a cell surface marker associated with immune cell function. This antibody, conjugated with FITC for easy detection, is suitable for use in flow cytometry and immunofluorescence assays. It specifically targets the KLRG-1 protein in both human and mouse samples, allowing for precise identification and analysis of KLRG-1-expressing cells in various research settings.KLRG-1, also known as killer cell lectin-like receptor G1, is a key marker for identifying specific subsets of immune cells, particularly cytotoxic T cells and natural killer cells.

Its expression patterns are indicative of cell differentiation and functional status, making it a valuable tool for studying immune responses in infection, inflammation, and cancer. By utilizing the FITC Anti-Human/Mouse KLRG-1 Antibody (2F1), researchers can gain insights into immune cell populations and their roles in immune surveillance and defense mechanisms.

Product Title:FITC Anti-Human/Mouse KLRG-1 Antibody [2F1]
SKU:AGEL3107
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2F1
Synonyms:MAFA; 2F1-Ag;
Host Species:Syrian Hamster
Reactivity:Human;Mouse
Application:FCM
Isotype:Syrian Hamster IgG
Isotype Control:FITC Syrian Hamster IgG Isotype Control[SHG-1]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q96E93 O88713
Gene ID:10219,50928
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG4 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

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