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Key Features

FITC Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL2172)

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SKU AGEL2172
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone M1/70
Conjugation FITC
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Description

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FITC Anti-Mouse/Human CD11b Antibody [M1/70]

The FITC Anti-Mouse/Human CD11b Antibody (M1/70) offered by AssayGenie is a highly specific tool for research involving CD11b, a cell surface marker expressed on macrophages, granulocytes, and natural killer cells. This antibody, conjugated with FITC for fluorescent labeling, allows for accurate detection and visualization of CD11b in both mouse and human samples.CD11b, also known as integrin alpha M, plays a crucial role in cell adhesion and migration, particularly in the immune response and inflammation processes. By targeting CD11b, researchers can investigate the functions and interactions of immune cells in various biological contexts.

This antibody is validated for use in flow cytometry applications, providing a powerful tool for studying immune cell populations and their involvement in immunity, inflammation, and disease progression.Whether studying immune cell behavior in infection, inflammation, or cancer, the FITC Anti-Mouse/Human CD11b Antibody (M1/70) from AssayGenie offers a reliable and specific reagent for precise detection and analysis of CD11b expression, contributing to advancements in immunology and related fields.

Product Title:FITC Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL2172
Size:25µg, 100µg
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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