The FOXD2 Polyclonal Antibody (PAC017887) is a valuable tool for researchers studying FOXD2, a transcription factor involved in developmental processes and cell differentiation. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in applications such as Western blotting.FOXD2 plays a crucial role in gene regulation and cellular processes such as embryonic development and tissue differentiation. Research involving FOXD2 is important in understanding its function in various biological processes, including cancer progression, stem cell maintenance, and neurodevelopmental disorders.
With its high reactivity and specificity, the FOXD2 Polyclonal Antibody is an essential reagent for studying the role of FOXD2 in normal development and disease states. It provides researchers with a valuable tool for investigating the molecular mechanisms underlying FOXD2 function and its potential as a therapeutic target in various medical conditions.
Antibody Name:
FOXD2 Antibody (PACO17887)
Antibody SKU:
PACO17887
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:15-1:50
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human FOXD2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17887(FOXD2 Antibody) at dilution 1/10, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOX (Forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. Many FOX proteins are important to embryonic development.
Synonyms:
forkhead box D2
UniProt Protein Function:
FOXD2: Probable transcription factor involved in embryogenesis and somatogenesis.Protein type: DNA-binding; Cell development/differentiation; Transcription factorChromosomal Location of Human Ortholog: 1p34-p32Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activityBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
