The Fyn Monoclonal Antibody (CAB9165) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is specifically reactive with human samples and is validated for use in various applications, including Western blotting and immunohistochemistry.FYN is a key regulator of various cellular processes, including cell growth, differentiation, and immune response modulation. Its role in signaling pathways makes it a crucial target for research in immunology, oncology, and neurology. By detecting and analyzing the FYN protein in different cell types, researchers can gain insights into its function and potential implications in disease mechanisms.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Fyn Monoclonal Antibody
SKU:
CAB9165
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1459
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SLK, SYN, p59-FYN, Fyn
Positive Sample:
HeLa, Jurkat, Mouse lung, Mouse testis, Mouse brain, Rat brain
Cellular Localization:
Cell Membrane, Cytoplasm, Nucleus.
Calculated MW:
61kDa
Observed MW:
59kDa
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Purification Method
Affinity purification
Gene ID
2534
RRID
AB_2863676
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Fyn Rabbit mAb (CAB9165) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1min.
