The GAB1 Antibody (CAB6248) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and is perfect for use in Western blot applications. By binding to Gab1, this antibody allows for the detection and analysis of Gab1 expression in various cell types.Gab1 is known for its role in regulating cell growth, survival, and differentiation, making it a key player in processes like development and cancer progression.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GAB1 Antibody
SKU:
CAB6248
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
DFNB26, GAB1
Positive Sample:
SH-SY5Y
Cellular Localization:
Cell-Cell Junction, Cytoplasm, Cytosol.
Calculated MW:
77kDa
Observed MW:
110kDa
The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
2549
RRID
AB_2766855
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using GAB1 Rabbit pAb (CAB6248) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 80s.
