The GCGR Antibody (CAB10617) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific to GCGR and is validated for use in various applications, including Western blotting and immunohistochemistry.GCGR is primarily expressed in the liver and pancreas and plays a key role in regulating glucose production and release. Dysregulation of GCGR signaling is associated with conditions such as diabetes and metabolic disorders, making it a promising target for therapeutic intervention.
This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GCGR Antibody
SKU:
CAB10617
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GGR, GL-R, MVAH, GCGR
Positive Sample:
293T, HepG2, Mouse liver, Mouse stomach, Rat liver, Rat heart
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
54kDa
Observed MW:
54kDa
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).
Purification Method
Affinity purification
Gene ID
2642
RRID
AB_2769589
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GCGR Rabbit pAb (CAB10617) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Western blot analysis of various lysates using GCGR Rabbit pAb (CAB10617) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
