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GenieFluor 488 Anti-Human CD40 Antibody [3A8] (AGEL2797)

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SKU AGEL2797
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2a, κ
Clone 3A8
Conjugation AF488
€95 - €413
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Description

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GenieFluor 488 Anti-Human CD40 Antibody [3A8]

The GenieFluor 488 Anti-Human CD40 Antibody (3A8) offered by Assay Genie is a cutting-edge tool for researchers studying CD40, an essential cell surface molecule involved in immune responses and inflammation. This antibody, optimized for use in human samples, is specifically designed to target CD40 protein, enabling precise detection and analysis in a variety of cell types.CD40 is a crucial immune receptor that plays a pivotal role in activating immune cells and modulating immune function. By targeting CD40 with the 3A8 antibody, researchers can delve deep into understanding the intricate mechanisms of immune regulation, paving the way for advancements in immunology, cancer research, and therapeutic development.

The GenieFluor 488 Anti-Human CD40 Antibody (3A8) is a reliable choice for experiments such as immunofluorescence, flow cytometry, and immunohistochemistry. Its high specificity and sensitivity ensure accurate and reproducible results, making it an indispensable tool for unraveling the complexities of immune responses and potential therapeutic targets. Trust Assay Genie's expertise to elevate your research with the GenieFluor 488 Anti-Human CD40 Antibody (3A8).

Product Title:GenieFluor 488 Anti-Human CD40 Antibody [3A8]
SKU:AGEL2797
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3A8
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 488 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25942
Gene ID:958
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

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