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GenieFluor Red 780 Anti-Human CD127/IL-7RA Antibody [A019D5] (AGEL3364)

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SKU AGEL3364
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, k
Clone A019D5
Conjugation AFRed 780
€144 - €532
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Description

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GenieFluor Red 780 Anti-Human CD127/IL-7RA Antibody [A019D5]

The GenieFluor Red 780 Anti-Human CD127 (IL-7RA) Antibody (A019D5) is a cutting-edge tool designed for researchers conducting studies involving the CD127 (IL-7RA) protein, a vital component in the regulation of immune responses and cell proliferation. This antibody, specifically developed for use in human samples, has been meticulously validated for various applications, including flow cytometry and immunofluorescence assays.CD127, also known as the interleukin-7 receptor alpha chain, is a crucial receptor involved in the growth and survival of immune cells, particularly T cells. Its significance in orchestrating immune responses and maintaining immune cell homeostasis makes it a key target for investigations in immunology, cancer biology, and autoimmune diseases.

By precisely binding to CD127, this antibody enables accurate detection and analysis of the protein in diverse cell types, providing invaluable insights into immune system function and potential therapeutic interventions.Researchers delving into immune cell signaling pathways, T cell development, and immune system dysregulation will find the GenieFluor Red 780 Anti-Human CD127 (IL-7RA) Antibody (A019D5) to be an indispensable tool for advancing their research endeavors. This antibody promises reliability, sensitivity, and specificity, making it an indispensable asset in unraveling the intricate mechanisms governing immune responses and cell dynamics.

Product Title:GenieFluor Red 780 Anti-Human CD127/IL-7RA Antibody [A019D5]
SKU:AGEL3364
Size:20 Tests, 100 Tests, 200 Tests
Clone No:A019D5
Synonyms:Interleukin-7 receptor subunit alpha;IL-7RA;CDw127;CD127;IL-7Rα;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16871
Gene ID:3575
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

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