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GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody [2F1] (AGEL3134)

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SKU AGEL3134
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Reactivity Mouse
Host Species Syrian Hamster
Isotype Syrian Hamster IgG
Clone 2F1
Conjugation AFViolet 450
€113 - €325
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Description

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GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody [2F1]

The GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody (2F1) from AssayGenie (Catalog No. AGEL3134) is a cutting-edge tool for immunological research applications. This high-quality antibody is specifically engineered to detect and target KLRG-1, a cell surface protein associated with immune responses and the regulation of T cell function in both human and mouse samples.KLRG-1, also known as killer cell lectin-like receptor G1, is a key marker in immunology research, providing insights into T cell differentiation and function in various biological processes. This antibody, produced through advanced techniques, offers exceptional sensitivity and specificity, allowing for precise detection and analysis of KLRG-1 expression in different cell types and tissues.

With its superior performance in techniques such as flow cytometry and immunofluorescence, the GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody (2F1) is an invaluable tool for researchers investigating immune responses, T cell biology, and related pathways. Its versatility and reliability make it an essential component for studies aiming to elucidate the role of KLRG-1 in health and disease, including cancer, infectious diseases, and autoimmunity.Choose AssayGenie's GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody (2F1) for robust and accurate detection of KLRG-1, empowering your research endeavors with exceptional quality and performance.

Product Title:GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody [2F1]
SKU:AGEL3134
Size:25µg, 100µg
Clone No:2F1
Synonyms:MAFA; 2F1-Ag;
Host Species:Syrian Hamster
Reactivity:Human;Mouse
Application:FCM
Isotype:Syrian Hamster IgG
Isotype Control:Genie Fluor Violet 450 Syrian Hamster IgG Isotype Control[SHG-1]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q96E93 O88713
Gene ID:10219,50928
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG33 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

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