The GIMAP4 Polyclonal Antibody (PACO00852) is a valuable tool for researchers studying GIMAP4, a member of the GTPase family with important roles in immune cell function. This antibody, produced in rabbits, shows high specificity for human samples and is validated for use in Western blot experiments. By binding to the GIMAP4 protein, researchers can easily analyze and detect its expression in a variety of cell types, making it an ideal choice for immunology and cancer research studies.
GIMAP4 is known for its involvement in the regulation of immune cell survival and function, making it a promising target for investigating diseases such as cancer, autoimmune disorders, and inflammatory conditions. By understanding the mechanisms by which GIMAP4 influences immune responses, researchers can gain insights that may lead to the development of novel therapeutic strategies for these challenging health conditions.
Antibody Name:
GIMAP4 Antibody
Antibody SKU:
PACO00852
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human GIMAP4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
GIMAP4; IAN1; IMAP4; MSTP062; GTPase IMAP family member 4; Immunity-associated nucleotide 1 protein; IAN-1; hIAN1; Immunity-associated protein 4
UniProt Protein Function:
GIMAP4: May play a role in regulating lymphocyte apoptosis. Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium. Belongs to the IAN GTP-binding protein family.Protein type: HydrolaseChromosomal Location of Human Ortholog: 7q36.1Cellular Component: cytosolMolecular Function: GTP binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
