The GNA14 Antibody (CAB10405) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GNA14 protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for investigations in signal transduction and molecular biology.GNA14 plays a key role in mediating intracellular signaling cascades, impacting processes such as cell proliferation, migration, and differentiation. Dysregulation of GNA14 has been implicated in various diseases, including cancer and neurological disorders, highlighting its importance as a potential therapeutic target.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GNA14 Antibody
SKU:
CAB10405
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HG1I, GNA14
Positive Sample:
BxPC-3, 293T, Mouse stomach, Mouse lung, Rat kidney
Cellular Localization:
Extracellular Exosome, Plasma Membrane.
Calculated MW:
42kDa
Observed MW:
41kDa
This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.
Purification Method
Affinity purification
Gene ID
9630
RRID
AB_2757954
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using GNA14 Rabbit pAb (CAB10405) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Immunofluorescence analysis of NIH/3T3 cells using GNA14 Rabbit pAb (CAB10405) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
