The GP2 Polyclonal Antibody (CAB6378) is a valuable tool for researchers studying GP2, a protein involved in immune regulation and gastrointestinal health. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the GP2 protein, this antibody allows for the detection and analysis of GP2 in a variety of cell types, making it ideal for studies in immunology and digestive system research.GP2 is known for its role in promoting immune tolerance in the gut and maintaining a healthy gut microbiome.
Dysregulation of GP2 has been linked to inflammatory bowel diseases and other gastrointestinal disorders, highlighting the importance of understanding its function. The GP2 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of GP2 in health and disease, paving the way for potential therapeutic interventions targeting this protein.
Product Name:
GP2 Polyclonal Antibody
SKU:
CAB6378
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 111-387 of human GP2 (NP_001007243.2).
This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2813
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of U-251MG cells, using GP2 antibody (CAB6378) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
