The GPR12 Polyclonal Antibody (PAC03922) is a valuable tool for researchers studying GPR12, a G protein-coupled receptor involved in various physiological processes, including modulation of hormone secretion and neuronal signaling. This antibody, generated in rabbits, demonstrates high specificity towards human samples and is validated for use in Western blot and immunohistochemistry applications.GPR12 is known to play a role in regulating neuroendocrine functions and has been implicated in several diseases, including cancer and neurological disorders.
By targeting GPR12 with this polyclonal antibody, researchers can detect and analyze the expression of this receptor in different cell types, providing insights into its function and potential therapeutic implications.With its ability to assist in the investigation of GPR12 in various research areas, including neuroscience, endocrinology, and cancer biology, the GPR12 Polyclonal Antibody (PAC03922) is a valuable tool for advancing our understanding of GPR12-related pathways and identifying potential targets for novel therapeutic interventions.
Antibody Name:
GPR12 Antibody
Antibody SKU:
PACO03922
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human GPR12.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
GPR12; G-protein coupled receptor 12
UniProt Protein Function:
GPR12: Promotes neurite outgrowth and blocks myelin inhibition in neurons. Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 13q12Cellular Component: integral to plasma membraneMolecular Function: G-protein coupled receptor activity; phosphatidylcholine bindingBiological Process: cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway
