The GPR132 Antibody (PAC06497) from Assay Genie is a valuable tool for researchers studying GPR132, a G protein-coupled receptor involved in immune regulation and inflammation. This polyclonal antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.GPR132, also known as OGR1 or G2A, plays a crucial role in immune responses and has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions.
By targeting GPR132 with this antibody, researchers can gain insight into its function and potential as a therapeutic target.With its high specificity and versatility in detecting GPR132 in different cell types, the GPR132 Antibody (PAC06497) is a valuable tool for advancing research in immunology, cancer biology, and drug development. Order yours today from Assay Genie to enhance your research in immune regulation and inflammation.
Antibody Name:
GPR132 Antibody (PACO06497)
Antibody SKU:
PACO06497
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
ELISA:1:5000, WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Monkey
Immunogen:
Synthesized peptide derived from the C-terminal region of human G2A.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of various cells using G2A Polyclonal Antibody.
Western Blot analysis of 293T cells using G2A Polyclonal Antibody.
Synonyms:
GPR132; G2A; Probable G-protein coupled receptor 132; G2 accumulation protein
UniProt Protein Function:
May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton-sensing activity.
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
