The GPR176 Polyclonal Antibody (PACO35518) is a valuable tool for researchers studying the GPR176 protein, a G protein-coupled receptor involved in various physiological processes. This antibody, produced in rabbits, exhibits high specificity for human samples and is ideal for use in Western blot applications. By binding to the GPR176 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a reliable choice for studies in neuroscience, endocrinology, and pharmacology.
GPR176 is known to play a role in regulating neurotransmitter release, hormone secretion, and cellular signaling pathways, making it a promising target for research into neurological disorders, endocrine dysfunctions, and drug development. Understanding the function and regulation of GPR176 is essential for unraveling its implications in health and disease, and this antibody provides a valuable tool for investigating its mechanisms of action.
Western blot. All lanes: GPR176 antibody at 10µg/ml + A431 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 57, 53 kDa. Observed band size: 57 kDa.
Immunofluorescent analysis of A431 cells using PACO35518 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-α and has an agonist-independent basal activity to repress cAMP production.
Synonyms:
G-protein coupled receptor 176 (HB-954), GPR176
UniProt Protein Function:
Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production.
UniProt Protein Details:
NCBI Summary:
Members of the G protein-coupled receptor family, such as GPR176, are cell surface receptors involved in responses to hormones, growth factors, and neurotransmitters (Hata et al., 1995 [PubMed 7893747]).[supplied by OMIM, Jul 2008]
